In as we speak’s health-conscious world, dietary dietary supplements have change into a well-liked instrument for filling dietary gaps, bettering general well-being, and even managing particular well being situations. Nonetheless, not all dietary supplements are created equal. Some could be contaminated, work together with drugs, and even hurt liver well being. Choosing the proper complement requires cautious consideration and consciousness of potential dangers, and it additionally means being conscious of shady advertising and marketing ways!
‘Dietary supplements’ is an umbrella time period for supplemental types of particular person vitamins like calcium and iron. However the extra problematic of the bunch are ‘pure’ dietary dietary supplements which can be marketed with shady claims, proprietary formulation, and little to no testing. These are the varieties of dietary supplements that I’m principally referring to on this put up.
The Hidden Risks of Dietary supplements: Liver Failure, Current Analysis, and The right way to Keep Secure
Dietary dietary supplements are a multi-billion-dollar trade, marketed as a simple approach to enhance well being, improve power, and fill in dietary gaps. Nonetheless, behind the shiny labels and well being claims, a rising physique of analysis reveals that some dietary supplements can pose critical well being dangers—together with liver failure.

In recent times, instances of supplement-induced liver harm (SILI) have been on the rise, with sure natural and dietary dietary supplements linked to extreme liver injury, hospitalization, and even loss of life. Regardless of being broadly accessible over-the-counter and infrequently perceived as “pure” and secure, many dietary supplements are poorly regulated and may comprise dangerous elements.
Complement Advertising is a Dumpster Hearth
‘Nevertheless it’s pure!’ So are toxic mushrooms, however no one needs to eat these. The complement trade – specifically the diet complement trade – is constructed on convincing folks to purchase dietary supplements that we really don’t want.
Implying that dietary supplements are extra ‘pure’ than drugs works on the Enchantment to Nature fallacy, which complement makers use to make their product seem safer than prescription drugs. As a dietitian, I’m seeing this so much with GLP-1 dietary supplements, that are principally simply rubbish. Nothing about them is efficient or safer than precise drugs, that are regulated and prescribed underneath managed situations (ideally…everyone knows one thing who’s getting them from doubtful sources).
I used to be unreasonably completely satisfied to see that Kourtney Kardashian’s Lemme GLP-1 complement is at the moment the topic of a category motion lawsuit for claiming to work like GLP-1 agonist treatment. It doesn’t. However as I wrote in one among my latest posts, there are various individuals who need GLP-1 treatment however can’t afford it. This leaves a niche that’s being grossly exploited by the complement trade.


That’s how shady complement makers earn their cash, and it typically works…to the tune of $177 billion {dollars} in 2023, and projected to develop exponentially for the forseeable future. Whether or not it’s weight reduction, menopause, blood sugar (see my Glucose Goddess Anti Spike assessment right here), immunity-boosting, or no matter else, the complement trade has a capsule for that.
It goes with out saying that if a complement is claiming to treatment nervousness or despair or every other psychological well being analysis, it’s an enormous purple flag. Claims like these are unethical and probably harmful, as they will persuade folks to desert efficient and mandatory treatment.
Getting sensible to complement advertising and marketing scams takes just a few small checks.
Vitamin Complement Crimson Flags:
No analysis, or basing claims on animal or cell analysis. Even in the event you aren’t well-versed in studying analysis, at all times check out the complement’s web site to see if it provides analysis to again up its claims. Is the analysis accomplished on people? Animals? How outdated are the research? Is the analysis accomplished on the product itself, or solely on sure elements that the product accommodates?
I wrote a put up about the fundamentals of deciphering diet analysis right here, however the TL;DR is that you really want latest research (as in, final 5 years), accomplished in people, printed in peer-reviewed journals, on the product itself. 99% of the time, you gained’t discover all of these issues. That may be a purple flag.
Something offered by multi-level advertising and marketing. Not solely do MLM corporations prey on weak folks (primarily ladies), they have an inclination to take advantage of egregious claims about their merchandise. MLM salespeople will not be educated to provide diet recommendation or perceive your well being historical past. Belief me – if one thing groundbreaking exists, it is going to be regulated by the FDA and offered in drugstores, not by some MLM coach.


Implying that their method was found by ‘Harvard (or X Ivy League) scientists’ or that Huge Pharma/precise scientists haven’t but found this groundbreaking secret. I see this so much from corporations like VShred (learn my VShred assessment right here) and Lifevantage (learn my Lifevantage Protandim and GLP-1 assessment right here), amongst many others. There isn’t any massive secret. No one is hiding something (moreover these corporations attempting to cover their grift, though they aren’t fooling me!). Identify dropping an Ivy League college by no means means something, both. It’s all bluster created to provide them false legitimacy.
Claiming {that a} complement can treatment the incurable, equivalent to autism, ADHD. Don’t even go there.
Huge claims and use of statistics that appear too good to be true. 95% of individuals love this complement? How did the corporate even decide that? Trace: they didn’t.


Using earlier than and after pictures and testimonials to ‘show’ efficacy of a product. These are simply faked, they usually present up when an organization has nothing higher to supply when it comes to proof of their product working.
The declare of being safer, extra pure, or equally efficient as precise drugs. We talked about this above.


Obscure claims utilizing phrases or phrases like ‘helps metabolism’ or ‘helps with X’. That is how corporations could make the claims they make, with out triggering the FDA’s consideration. It’s a loophole that many individuals don’t find out about, however now you do!
Using influencers to promote the product. This one is perhaps controversial, however I really feel like well-liked influencers utilizing affiliate codes to flood peoples’ social feeds with advertisements for a product is a distraction and made to persuade potential clients that in the event that they use the product, they’ll be younger/engaging/wholesome/well-liked just like the folks promoting it.
The Risks of Vitamin Dietary supplements
Whereas all diet dietary supplements are marketed as helpful, they will typically do extra hurt than good. Among the key dangers embody:
Lack of Regulation
The U.S. Meals and Drug Administration (FDA) regulates dietary supplements underneath the Dietary Complement Well being and Training Act (DSHEA) of 1994, which permits producers to promote merchandise with out proving their security or efficacy. In contrast to pharmaceuticals, dietary dietary supplements will not be required to endure rigorous testing earlier than hitting the market.
Because of this:
Dietary supplements could comprise unlisted or dangerous elements.
Dosages could also be inconsistent or greater than really helpful.
Contaminants equivalent to heavy metals, pesticides, or pharmaceuticals could also be current.
The FDA usually doesn’t get entangled except there has really been hurt accomplished to an individual by the complement.


Liver Toxicity and Organ Harm
The liver performs a vital function in processing dietary supplements, breaking down compounds, and detoxifying dangerous substances. Nonetheless, sure dietary supplements comprise elements that may overwhelm or injury liver cells, resulting in:
Hepatotoxicity (liver toxicity): The liver struggles to course of poisonous compounds, resulting in irritation and cell injury.
Acute liver failure: Extreme instances the place the liver loses its capability to perform, typically requiring a transplant or leading to loss of life.
Continual liver illness: Lengthy-term injury from repeated publicity to dangerous dietary supplements.
Harmful Interactions with Drugs
Many individuals take dietary supplements alongside prescription drugs with out realizing that sure mixtures could be poisonous.
For instance, St. John’s Wort can cut back the effectiveness of antidepressants and contraception capsules. Kava and inexperienced tea extracts have been linked to extreme liver injury, particularly when taken with different drugs metabolized by the liver. Vitamin A and iron in extreme doses could cause liver irritation and injury.
Current Analysis on Complement-Induced Liver Failure
Over the previous decade, scientific research and scientific experiences have highlighted a regarding rise in supplement-related liver harm.


The DILIN Examine (2014 – Current)
The Drug-Induced Liver Harm Community (DILIN), a U.S.-based analysis initiative, has been monitoring instances of drug- and supplement-related liver harm.
Their findings present that:
Natural and dietary dietary supplements account for 20% of liver harm instances within the U.S.
The speed of supplement-induced liver injury has elevated from 7% in 2004 to twenty% lately.
Weight-loss and bodybuilding dietary supplements are probably the most generally implicated.
Inexperienced Tea Extracts and Hepatotoxicity
Inexperienced tea extract is a well-liked complement discovered in lots of weight-loss merchandise, however analysis has linked it to extreme liver toxicity.
A 2018 examine within the journal Hepatology discovered that catechins, the energetic compounds in inexperienced tea, could cause liver injury in excessive doses. Some instances resulted in acute liver failure requiring transplants. A 2022 examine discovered garcinia cambogia, with or with out inexperienced tea (I’ve seen numerous dietary supplements that comprise each of those elements) could cause reasonable to extreme liver harm.


Bodybuilding Dietary supplements and Undisclosed Steroids
Bodybuilding dietary supplements are among the many most harmful, with many containing undeclared anabolic steroids that may trigger liver toxicity.
A 2017 examine in The Journal of Gastroenterology and Hepatology discovered that:
Almost 50% of liver harm instances in younger males had been linked to bodybuilding dietary supplements.
Many of those dietary supplements contained unlawful or undisclosed steroid compounds.
Heavy metals like arsenic, micro organism and fungi, banned stimulants like ephedrine, and undeclared medication like sibutramine (discovered to have cardiac dangers) are only some examples of what has lately been present in natural diet dietary supplements.
Whereas not all dietary supplements are dangerous, it’s important to method them with warning. Right here’s easy methods to defend your self:
Do Your Analysis Earlier than Taking Any Complement
Search for scientific research that help the security and effectiveness of a complement.
Be skeptical of merchandise that promise fast weight reduction, excessive muscle achieve, or “detox” advantages. If one thing is promising to do what no different complement or treatment has accomplished earlier than (ie fats burners), stroll or scroll proper on by. Whereas a complement won’t be harmful, I additionally contemplate the monetary impacts of taking something you don’t really want.


Select Third-Get together Examined Dietary supplements
For the reason that FDA doesn’t regulate dietary supplements strictly, search for third-party testing from organizations equivalent to:
U.S. Pharmacopeia (USP)
NSF Worldwide
ConsumerLab
These certifications be certain that dietary supplements comprise what they declare and would not have dangerous contaminants.
Keep away from Excessive-Danger Dietary supplements
Among the most harmful dietary supplements embody:
Inexperienced tea extract (excessive doses)
Kava
Kratom
Bodybuilding dietary supplements with steroids
Weight-loss dietary supplements with “fats burners” or stimulants
Speak to Your Physician Earlier than Utilizing Dietary supplements
If you’re on drugs, ask your physician about doable complement interactions.
You probably have liver illness, diabetes, or coronary heart situations, be additional cautious with dietary supplements.
In Brief:
Dietary dietary supplements could be useful in some instances, however in addition they pose important dangers—particularly to liver well being. With analysis linking sure dietary supplements to liver failure, it’s essential to learn and selective about what you’re taking.
By selecting third-party examined merchandise, avoiding high-risk dietary supplements, and prioritizing entire meals, you’ll be able to defend your liver and general well being. At all times seek the advice of with a healthcare skilled earlier than including any new complement to your routine.
Your well being is value greater than a fast repair—keep knowledgeable, and keep secure!