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Advil or Tylenol? Which painkiller to take and when : NPR


Many over-the-counter ache drugs can be found, however are all of them the identical? And the way a lot must you actually take?

Picture illustration by Beck Harlan/NPR


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Picture illustration by Beck Harlan/NPR

When hit with a headache or fever, individuals usually attain for over-the-counter painkillers like acetaminophen or nonsteroidal anti-inflammatory medicine (NSAIDs) as their first line of protection.

Used accurately, these medicine will be protected and efficient for ache aid. Meaning following the directions on the label and the recommendation of a well being care supplier.

«However that is not how we take these drugs in actual life,» says Trisha Pasricha, a doctor and teacher at Harvard Medical College. Some individuals take an excessive amount of ache medicine too rapidly, misdiagnose an ailment and take the fallacious drug, or unknowingly take a number of ache relievers on the identical time.

One research printed in 2018, for instance, discovered that 15% of over 1,300 survey contributors exceeded every day NSAID dosages, and most contributors did not acknowledge that every one the merchandise they have been taking have been NSAIDs.

These behaviors can result in severe unwanted effects, from bloating and nausea all the way in which as much as coronary heart assault and stroke, Pasricha says.

To stop these dangers, the well being care professionals we spoke to for this story say it is essential to get to know the painkillers in your drugs cupboard. Listed here are 10 issues they need you knew about these medicine.

1. Acetaminophen is often the higher alternative for fevers, says College of California San Francisco (UCSF) medical pharmacist Sweet Tsourounis. Generally referred to as Tylenol, it is thought to scale back fever and relieve minor aches and pains by elevating your physique’s ache threshold and regulating your physique temperature. It is also gentler on the physique than NSAIDs are.

2. NSAIDs are usually thought-about more practical than acetaminophen for ache aid, Tsourounis says, particularly for inflammatory ache like muscle aches. Whereas acetaminophen is believed to work solely on the central nervous system, NSAIDs equivalent to aspirin, ibuprofen (like Advil or Motrin) or naproxen (like Aleve) work all through the physique to scale back irritation, ache and fever.

3. Taking an excessive amount of acetaminophen at one time or too many doses shut collectively could cause liver harm, Tsourounis says. So stick to three,000 milligrams of the drug at most per day, and do not combine it with alcohol, which can be exhausting on the liver.

4. NSAIDs carry dangers to the intestine and the center. Widespread unwanted effects embody abdomen ache, heartburn and bloating. It’s also possible to expertise extra severe harm like ulcers, gastrointestinal bleeding or kidney harm if you happen to take NSAIDs at too excessive a dose and even only for too lengthy a time interval, Pasricha says. And non-aspirin NSAIDs have the potential to lift your blood stress. Each NSAID has a unique max dose, so take note of your labels.

5. When you’re unsure which painkiller to make use of or how a lot to take, speak to a pharmacist, says Blamoh Twegbe, pharmacy supervisor at UCSF outpatient pharmacy. «Please make the most of us. That is what we’re right here for!» They may also help you make an knowledgeable choice by asking about your sort of ache and power circumstances and by checking any potential drug interactions.

6. There is a restrict to how a lot ache NSAIDs can deal with, Pasricha says. When you take greater than the really useful dosage or multiple sort of NSAID without delay — for instance, combining Motrin and Aleve — you are rising your danger of unwanted effects with out getting any further ache aid. When you really feel your over-the-counter (OTC) medicine aren’t working, speak to a health care provider or pharmacist as an alternative of ignoring the warning label.

This photo shows a blue and white daily pill container filled with Aleve and Tylenol for each day of the week, on a pink backdrop.

When you’re recurrently taking the identical over-the-counter ache drugs, speak to your physician about options that may higher tackle your signs.

Picture illustration by Beck Harlan/NPR


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Picture illustration by Beck Harlan/NPR

7. When you’re habitually reaching for a similar OTC ache medicine, speak to your well being care supplier. For instance, if you happen to’re taking naproxen on daily basis of your interval each month due to muscle cramps. Pasricha says that ache would possibly sign a bigger underlying well being drawback that might be higher handled with prescription medicine, way of life modifications or each.

8. Watch out for by accident overmedicating with a mix OTC medicine. Acetaminophen and NSAIDs are sometimes included in lots of different sick-day cures, like migraine medicine, allergy drugs or all-in-one chilly and flu medicines, Twegbe says. So while you’re not feeling properly, double-check your labels earlier than assuming you want a dose of Tylenol on high of these cold-relief meds.

This close-up photo shows rows of pills alternating between acetaminophen (white circular pill) and ibuprofen (orange oval pill) on a bright orange background with a strong shadow.

Alternating between acetaminophen and an NSAID like ibuprofen will be protected and efficient for ache administration.

Picture illustration by Beck Harlan/NRP


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Picture illustration by Beck Harlan/NRP

9. Alternate between NSAIDs and acetaminophen to handle main ache and cut back unwanted effects. When you’re affected by the flu or nursing a brand new damage and wish robust and regular ache aid, switching between acetaminophen and an NSAID like ibuprofen each few hours could be a protected and efficient method that will help you cope till your signs subside, Twegbe says. Simply ensure that to observe really useful dosages and dosing instances for every medicine.

10. Suppose past drugs.  As a result of over-the-counter ache relievers are so available, individuals usually neglect that drugs aren’t the one possibility when affected by minor aches and pains, Pasricha says. Many NSAIDs and different analgesics can be found in topical kind, like lotions or patches, and may supply comparable aid with out the potential unwanted effects to your intestine.

There are additionally nonmedication cures, like heating pads to ease again ache or exercising in water for arthritis. Discuss to your physician about your options, Pasricha says. «They could even management your ache extra reliably than simply taking drugs.»

The digital story was edited by Malaka Gharib. The visible editor is Beck Harlan. We would love to listen to from you. Depart us a voicemail at 202-216-9823, or electronic mail us at LifeKit@npr.org.

Take heed to Life Equipment on Apple Podcasts and Spotify, and join our e-newsletter. Comply with us on Instagram: @nprlifekit.



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